‎DUBUT DE LAFOREST‎
‎MORPHINE‎

‎Analyse de l'Opium. De la Morphine et de l'Acide méconique, considérés comme parties essentielles de l'Opium.‎

‎Paris, Crochard, 1817. No wrappers. Extract from ""Annales de Chimie et de Physique, Par MM. Gay-Lussac et Arago."", tome 5, Cahier 1. With titlepage and htitle to vol. 5. Pp. 21-42.‎

‎First French edition (the German paper issued simutaneously in Gilbert's Annalen) of this groundbreaking paper claiming to be the first to announce the isolation of pure morphine from opium. This process marks an importent step in the beginnings of alkaloid chemistry, and the isolation of morphine is the first isolation of an alkali of vegetable origin. In his paper Sertuerner coined the word ""morphine"" after Morpheus (the Greek God of sleep).The isolation of morphine from opium, the first isolation of a natural product, was a seminal event in the development of pharmacology as an independent discipline. The purification kick-started natural product chemistry and quickly led to the isolation of a host of other alkaloids. Within a few years, in 1827, Heinrich Emanuel Merck of Darmstadt began selling morphine, resulting in the development of the eponymous company. Sertürner reported his first observations on Opium in 1805, which was mainly concerned with the constituent of meconic acid, but ""it was only in 1817...(in the paper offered) that he unequivocally reported the isolation of pure morphine. He prepared it by extracting opium with hot water and precipitating morphine with ammonia. he obtained colorless crystals, poorly soluble in water, but soluble in acids and alcohol. In order to establish that his crystals carried the pharmacological activity of raw opium, Sertuerner tested them on himself and three boys, ""none older than seventeen."". It was a near-catastrophe."" (Ryan J. Huxtable a. K.W. Schwarz).DEROSNE (1803) made claim of priority in the discovery of opium, but he only ""prepared a crude extract of opium with alcohol and water, and obtained by potassium carbonate preciipitation, what he called ""sel de Derosne"". Derosne's alkaloidal fraction lacked narcotic properties, and was probably largely narcotine (also known as noscapine), perhaps with meconic acid, both abundant in opium."" (Huxtable & Schwarz).Parkinson ""Breakthroughs"", 1817 C,The offered issue contains another importent paper by Alexander v. Humboldt: ""Sur les Lignes isothermes. (Extrait)"", pp. 102-111 and a large folded engraved plate. Here Humboldt introduced ""Isothermes"" in meteorology. This extract issued at the same time as the larger memoir which appeared in ""Mémoires de physique et de chimie de la Société d’Arcueil"" (1817).‎

‎Burkart R. Morfinism in the Public Interest: Chronic Morphine Poisoning and Trea‎

‎Burkart R. Morfinism in the Public Interest: Chronic Morphine Poisoning and Treatment by Gradual Morphine Withdrawal In Russian (ask us if in doubt)/Burkart R. Morfinizm v obshchedostupnom izlozhenii. Khronicheskoe otravlenie morfiem i lechenie posredstvom postepennogo otnyatiya morfiya St. Petersburg Library of National Health 1901. 31 p. SKUalbf458f84845054de7.‎

‎Du traitement curatif de la folie par le chlorhydrate de morphine. [avec : ] Nouvelles observations sur le traitement curatif de la folie par les injections sous-cutanées de chlorhydrate de morphine.‎

‎Paris, Doin, 1874, 1876.‎

‎ Illustré par 8 gravures dans le texte montrant des aliénés. Auguste-Félix Voisin (1829-1898) prit ses fonctions à la Salpétrière en 1867, où il a organisé des "Conférences cliniques sur les maladies mentales et les affections nerveuses". Il préconise ici l'emploi du chlorhydrate de morphine "à des doses importantes puisqu'elles atteignent quarante centigrammes par jour." (Postel, Quétel Nouvelle histoire de la psychiatrie 730.) Premières éditions séparées. Tirés à part du "Bulletin de thérapeutique médicale". Coiffes frottés, mais bon exemplaire. /// In-8 de 54 pp., 47 pp. Demi-chagrin bleu, dos orné. (Reliure de l'époque.) //// /// PLUS DE PHOTOS SUR WWW.LATUDE.NET‎

‎De l'Opium et de la Morphine - Leur emploi, leur utilité, leurs dangers - Guérison assurée des troubles psychiques et physiques du Morphinisme‎

‎Paris, Bibliothèque des curiosités H. Daragon, Editeur, 1908. 1 volume in-12, 84 pp., reliure moderne plein cuir noir, couvertures d'origine conservées, quelques rousseurs sur le premier plat et la page de garde, sinon bon état.‎

‎Table des matières: De l'opium - Dérivés du pavot et de l'opium - Emploi de l'opium en médecine - l'opium dans Pline - Les effets de l'opium - Pharmacopée d'Edimbourg et autres - Psychologie du fumeur d'opium - Les fumeries d'opium - l'opium interdit en Chine - la question de l'opium en Chine - de la thérique, sa composition - De la morphine et des morphinomanes - Anaphrodisie morphinique - Psychologie du morphinomane - Conclusion.‎

‎Kraevsky V.I. On the comparative influence of morphine and its various derivativ‎

‎Kraevsky V.I. On the comparative influence of morphine and its various derivatives (heroin peronin dionine and codeine) on respiratory activity and the general state of the body. In Russian (ask us if in doubt)/Kraevskiy V.I. O sravnitel'nom vliyanii morfiya i razlichnykh ego proizvodnykh (geroina peronina dionina i kodeina) na dykhatel'nuyu deyatel'nost' i obshchee sostoyanie organizma. Short description: In Russian (ask us if in doubt).Thesis. St. Petersburg 1902. 250 p. We have thousands of titles and often several copies of each title may be available. Please feel free to contact us for a detailed description of the copies available. SKUalbce62faa9c927bc88‎