‎Guine, Raquel‎
‎Vitamin C‎

‎Observation on the function of peroxidase systems and the chemistry of the adrenal cortex. Description of a new corbohydrate derivative. - [DISCOVERY OF VITAMIN C - NOBEL PRIZE 1937]‎

‎London, Cambridge University Press, 1928. Royal8vo. In the original printed wrappers. In ""The Biochemical Journal"", Vol. 22, 1928. Entire issue offered. Wrappers with nicks and ligt overall soiling. A tear to last 7 leaves. Internally fine and clean. Pp. 1387-1409. [Entire issue: Pp. (8), 1341-1575, (2), XIV, (1).].‎

‎First printing of Szent-Györgyi's landmark paper in which he for the first time discovered and isolated ""hexuronic acid"" or ""ascorbic acid"", today commonly known as vitamin C. In 1937 he was awarded the Nobel in Medicine ""for his discoveries in connection with the biological combustion processes, with special reference to vitamin C and the catalysis of fumaric acid"".""Szent-Györgyi is most notably associated with the discovery of vitamin C. The discovery of vitamins themselves was recognized in 1929 in a Nobel Prize to Christiaan Eijkman and Gowland Hopkins. The search for vitamin C was then well underway in several labs. Ironically, the compound had already been isolated by Szent-Györgyi. Though no one-not even Szent-Györgyi-yet knew its identity."" (DSB). ""In 1928 Szent-Györgyi had proposed that hexuronic acid, a highly reducing substance that he had isolated from oranges, cabbages and adrenal glands, was responsible for the anti-scurvy properties of fruit and vegetables, that is, that hexuronic acid was vitamin C. Zilva disagreed, citing work that he had done showing that vitamin activity and reducing power were independent of one another. There the matter lay for four years until, in 1932, Szent-Györgyi, carried out experiments to see whether hexuronic acid would protect guinea pigs from scurvy [which it indeed did]"". (Smith, Nutrition in Britain, P. 45). At the same time, for five years King's laboratory at the University of Pittsburgh had been trying to isolate the antiscorbutic factor in lemon juice using the original 1907 model of scorbutic guinea pigs which developed scurvy when not fed fresh foods but were cured by lemon juice. They had also considered hexuronic acid, but had been put off the trail when a coworker made the explicit (and mistaken) experimental claim that this substance was not the antiscorbutic substance. Finally, in late 1931, Szent-Györgyi gave Svirbely, formerly of King's lab, the last of his hexuronic acid with the suggestion that it might be the anti-scorbutic factor. By the spring of 1932, King's laboratory had proven this but published the result without giving Szent-Györgyi credit for it, leading to a bitter dispute over priority claims.Garrison & Morton 1059‎

‎Cholesterinstoffwechsel in Hühnereiern und Hühnchen. [In: Biochemische Zeitschrift: 215]. - [THE DISCOVERY OF VITAMIN K]‎

‎Berlin, 1929. 8vo. Entire volumes 215 and 216 of Biochemische Zeitschrift, bound in one half cloth binding with gilt lettering to spine.Library stamp to first 4 leaves. Traces after paper label to upper part of front board. Hindges a bit weak. Internally fine and clean. Pp. (475)-492. [Entire volumes: V,(1), 500 pp. + IV, 500 pp].‎

‎First printing of the documentation of the discovery of the dietary anti-haemorrhiagic factor, Vitamin K. The Danish biochemist and physiologist Henrik Dam (1895-1976) was awarded the Nobel Prize in Medicine in 1943 for joint work with Edward Doisy work in discovering vitamin K and its role in human physiology. Dam's key experiment involved feeding a cholesterol-free diet to chickens. It was thus that he in 1929 investigated the role of cholesterol, by feeding the chickens a cholesterol-depleted diet. After several weeks, the animals developed hemorrhages and started bleeding uncontrollably. The bleeding could not be stopped with purified cholesterol alone - a second compound had to be added to the food. Dam isolated this dietary substance needed for blood clotting, namely that which is now known as the coagulation vitamin or vitamin K. The new vitamin received the letter K because the initial discoveries were reported (here) in the German journal Biochemische Zeitschrift, in which it was designated as Koagulationsvitamin (Vitamin of Coagulation).G&M: 1062.‎

‎Vitamin C i profilaktika C-gipovitaminoznykh sostoyaniy na Severe. In Russian ‎

‎In Russian. Kiverin, Mikhail Dmitrievich. Vitamin C and the prevention of C-hypovitamin states in the North. Arkhangelsk: Seventh-century book-editions, 1971. Vitamin C i profilaktika C-gipovitaminoznykh sostoyaniy na Severe. In Russian /Vitamin C and C-Vitamin C Prevention in the North . All images are for identification of editions only. Several books of the same edition may be available. Please feel free to request photos of available books. SKU7393564‎

‎Selen, vitamin E i drugie biologicheski aktivnye veshchestva v profilaktike nÖ‎

‎In Russian. Kosmachev, Viktor Kuzmich. Selenium, vitamin E and other biologically active substances in the prevention of certain metabolic diseases. Moscow: VNIITEISH, 1974. Selen, vitamin E i drugie biologicheski aktivnye veshchestva v profilaktike nekotorykh zabolevaniy obmena veshchestv. In Russian /Selenium, vitamin E and other biologically active substances in the prevention of certain metabolic diseases. All images are for identification of editions only. Several books of the same edition may be available. Please feel free to request photos of available books. SKU7413743‎

‎Smith L. Vitamin B-12. In Russian (ask us if in doubt)/Smit L. Vitamin V-12.‎

‎Smith L. Vitamin B-12. In Russian (ask us if in doubt)/Smit L. Vitamin V-12.. Short description: In Russian (ask us if in doubt).Foreign Literature 1962. 176 p. We have thousands of titles and often several copies of each title may be available. Please feel free to contact us for a detailed description of the copies available. SKUalb439d842e797fa2dc‎