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"PELLETIER, PIERRE et JOSEPH CAVENTOU. - THE DISCOVERY OF STRYCHNINE.
Reference : 43871
(1818)
Note sur un nouvel Alcali (Lu à l'Academie des Sciences le 10 août 1818. (+) Mémoire Sur un nouvel Alcali végétal (la Strychine) trouvé dans la fève de Saint-Ignace, la noix vomique, etc. (Lu à l'Academie des Sciences le 14 décembre 1818).
(Paris, Crochard, 1818,1819). No wrappers. In: ""Annales de Chimie et de Physique, Par MM. Gay-Lussac et Arago."", tome 8 (Cahier 3) a. 10 ( Cahier 2), pp. 225-336 and pp. 129-240. (Entire issues offered). Pelletier & Caventou's papers: pp. 323-324 (tome 8) and pp. 142-176 (tome 10). A few scattered brownspots.
First printing of these classic papers in chemistry in which the authors announced their discovery of Strychnine. This was the first alkali of vegetable origin to be discovered after morphine. This discovery (and their discovery of chlorophyll) brought them international fame. The first small paper contains the announcement of the discovery and the second long memoir contains the elaborate exposition of the discovery.""Strychnine was only the second alkaloid to be extracted, the first was morphine. Pelletier and Caventou wanted to name their new alkaloid vauqueline after Nicolas Vauquelin, one of their associates who had refined the technique of ether extraction for use in isolating alkaloids. However, the officers of the Académe des Sciences in Paris rejected the idea on the grounds that a respected scientist’s name should not be paired with a deadly poison. In addition to strychnine the pair isolated other important compounds from plants including caffeine, chlorophyll and the anti-malaria drug quinine. (Paul L. Burnham).Parkinson:""Breakthroughs"", 1818 C. - Garrison & Morton: 1846.The first issue also contains their importent memoir ""Examen chimique de la Cochenillee et de sa matière colorante"", pp. 250-287 which describes how they obtained crotonic acid from croton oil and analyzed carmine in the cochineal.
Note sur un nouvel Alcali (Lu à l'Academie des Sciences le 10 août 1818. - [THE DISCOVERY OF STRYCHNINE]
Paris, Crochard, 1818. 8vo. In contemporary half calf. Wear to extremities and paperlabel pasted on to top to spine. In: ""Annales de Chimie et de Physique, Par MM. Gay-Lussac et Arago."", tome 8 (Cahier 3). Entire volume offered. Stamps to verso of title-page and verso of plates. (Pelletier & Caventou's paper): pp. 323-324. (Entire issue:) 448 pp. + 1 plate.
![Note sur un nouvel Alcali (Lu à l'Academie des Sciences le 10 août 1818. - [THE DISCOVERY OF STRYCHNINE]. "PELLETIER, PIERRE et JOSEPH CAVENTOU.](https://static.livre-rare-book.com/pictures/LLX/59820_1_thumb.jpg)
![Note sur un nouvel Alcali (Lu à l'Academie des Sciences le 10 août 1818. - [THE DISCOVERY OF STRYCHNINE]. "PELLETIER, PIERRE et JOSEPH CAVENTOU.](https://static.livre-rare-book.com/pictures/LLX/59820_2_thumb.jpg)
First printing of this classic paper in chemistry in which the authors announced their discovery of Strychnine. This was the first alkali of vegetable origin to be discovered after morphine. This discovery (and their discovery of chlorophyll) brought them international fame. ""Strychnine was only the second alkaloid to be extracted, the first was morphine. Pelletier and Caventou wanted to name their new alkaloid vauqueline after Nicolas Vauquelin, one of their associates who had refined the technique of ether extraction for use in isolating alkaloids. However, the officers of the Académe des Sciences in Paris rejected the idea on the grounds that a respected scientist’s name should not be paired with a deadly poison. In addition to strychnine the pair isolated other important compounds from plants including caffeine, chlorophyll and the anti-malaria drug quinine. (Paul L. Burnham). Parkinson:""Breakthroughs"", 1818 C. - Garrison & Morton: 1846. The first issue also contains their importent memoir ""Examen chimique de la Cochenillee et de sa matière colorante"", pp. 250-287 which describes how they obtained crotonic acid from croton oil and analyzed carmine in the cochineal.
Note sur un nouvel Alcali (Lu à l'Academie des Sciences le 10 août 1818. - [THE DISCOVERY OF STRYCHNINE]
Paris, Crochard, 1818. 8vo. In a bit later half cloth. In: ""Annales de Chimie et de Physique, Par MM. Gay-Lussac et Arago."", tome 8 (Cahier 3). Entire volume offered. No institutional stamps. Light occassional brownspotting, otherwise a good copy. (Pelletier & Caventou's paper): pp. 323-324. (Entire issue:) 448 pp. + 1 plate.
![Note sur un nouvel Alcali (Lu à l'Academie des Sciences le 10 août 1818. - [THE DISCOVERY OF STRYCHNINE]. "PELLETIER, PIERRE et JOSEPH CAVENTOU.](https://static.livre-rare-book.com/pictures/LLX/60069_1_thumb.jpg)
![Note sur un nouvel Alcali (Lu à l'Academie des Sciences le 10 août 1818. - [THE DISCOVERY OF STRYCHNINE]. "PELLETIER, PIERRE et JOSEPH CAVENTOU.](https://static.livre-rare-book.com/pictures/LLX/60069_2_thumb.jpg)
![Note sur un nouvel Alcali (Lu à l'Academie des Sciences le 10 août 1818. - [THE DISCOVERY OF STRYCHNINE]. "PELLETIER, PIERRE et JOSEPH CAVENTOU.](https://static.livre-rare-book.com/pictures/LLX/60069_3_thumb.jpg)
First printing of this classic paper in chemistry in which the authors announced their discovery of Strychnine. This was the first alkali of vegetable origin to be discovered after morphine. This discovery (and their discovery of chlorophyll) brought them international fame. ""Strychnine was only the second alkaloid to be extracted, the first was morphine. Pelletier and Caventou wanted to name their new alkaloid vauqueline after Nicolas Vauquelin, one of their associates who had refined the technique of ether extraction for use in isolating alkaloids. However, the officers of the Académe des Sciences in Paris rejected the idea on the grounds that a respected scientist’s name should not be paired with a deadly poison. In addition to strychnine the pair isolated other important compounds from plants including caffeine, chlorophyll and the anti-malaria drug quinine. (Paul L. Burnham). Parkinson:""Breakthroughs"", 1818 C. - Garrison & Morton: 1846. The first issue also contains their importent memoir ""Examen chimique de la Cochenillee et de sa matière colorante"", pp. 250-287 which describes how they obtained crotonic acid from croton oil and analyzed carmine in the cochineal.
"PELLETIER, PIERRE et JOSEPH CAVENTOU. - THE NAMING AND ISOLATION OF CHLOROPHYLL
Reference : 43741
(1818)
Sur la Matière verte des Feuilles.
(Paris, Crochard, 1818). No wrappers. In: ""Annales de Chimie et de Physique, Par MM. Gay-Lussac et Arago."", tome 9 (Sec. Cahier), pp. 113-224. (Entire issue offered). Pelletier & Caventou's paper: pp. 194-196. Clean and fine.
In this paper the two famous French chemists announced the first isolation of, and the naming of the substance Chlorofyll, the green substance essential for photosynthesis.Chlorophyll is the molecule that absorbs sunlight and uses its energy to synthesise carbohydrates from CO2 and water. This process is known as photosynthesis and is the basis for sustaining the life processes of all plants. Since animals and humans obtain their food supply by eating plants, photosynthesis can be said to be the source of our life also.
Analyse chimique des quinquina. Suivies d'observations médicales sur l'emploi de la quinine et de la cinchonine
Paris, chez L. Colas, 1821, in-8, VIII-88 pp, Demi-veau moderne brun clair, pièce de titre rouge en long, couvertures conservées, Première édition en librairie : cette analyse, qui démontre la manière dont les pharmaciens Pelletier (1788-1842) et Caventou (1795-1877), sont parvenus à isoler la quinine, est parue au préalable en février et en mars 1821, dans le tome VII du Journal de pharmacie et des sciences accessoires. Après avoir présenté leurs travaux devant l'Académie des sciences le 11 septembre 1820, ils les publient pour la première fois sous la forme de deux articles : "Recherches chimiques sur les quinquina" (février 1821) et "Examen chimique du quinquina carthagène (Portlandia hexandra)" (mars 1821). Pelletier et Caventou, qui étaient déjà parvenus à isoler la strychnine en 1819, mirent au point en 1820 une base cristallisée à partir d'échantillons de quinquina jaune : ils la nommèrent tout d'abord, Bertholine (en l'honneur du chimiste Berthollet), puis quinine. Ce fébrifuge d'une grande efficacité fit rapidement l'objet d'un commerce intense. La demande croissante conduisit à une véritable industrialisation du produit, première du genre en pharmacie. Pelletier en produira lui-même à grande échelle dans l'usine qu'il installera en 1824 à Clichy, avant de s'associer aux pharmaciens Delondre et Levaillant, avec lesquels il ouvrira une usine à Nogent-sur-Marne, qui sera l'une des principales fabriques de quinine au monde. Rousseurs et une mouillure angulaire sur les premiers feuillets. Bel exemplaire, néanmoins. Garrison & Morton n° 5233. Couverture rigide
Bon VIII-88 pp.
